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Robert Thoburn, MD

Robert ThoburnRobert Thoburn, MD
Adjunct Associate Professor of Medicine

Degree/Program

Institution

Field/Specialty

MD University of Florida
Residency Barnes Hospital, St. Louis, Missouri Internal Medicine
Fellowship Johns Hopkins Hosptial Infectious Disease
Fellowship Rockerfeller University, New York, NY Rheumatology

Clinical Interests:

  • Vasculitis
  • Autoimmunity

Research Interests:

  • Cellular mechanisms in vasculitis

Honors and Awards:

  • The Paulding Phelps Award, American College of Rheumatology
  •  Master, American College of Rheumatology

Publications:

  • Chen H, Zheng D, Ambadapadi S, Davids J, Ryden S, Samy H, Bartee M, Sobel E, Dai E, Liu L, Macaulay C, Yachnis A, Weyand C, Thoburn R, Lucas A. Serpin treatment suppresses inflammatory vascular lesions in temporal artery implants (TAI) from patients with giant cell arteritis. PLoS One. 2015 Feb 6;10(2):e0115482. PMID: 25658487.
  • Chen H, Zheng D, Abbott J, Liu L, Bartee MY, Long M, Davids J, Williams J, Feldmann H, Strong J, Grau KR, Tibbetts S, Macaulay C, McFadden G, Thoburn R, Lomas DA, Spinale FG, Virgin HW, Lucas A. Myxomavirus-derived serpin prolongs survival and reduces inflammation and hemorrhage in an unrelated lethal mouse viral infection.  Antimicrob Agents Chemother. 2013 Sep;57(9):4114-27. PMID: 23774438.
  • Chen H, Zheng D, Davids J, Bartee MY, Dai E, Liu L, Petrov L, Macaulay C, Thoburn R, Sobel E, Moyer R, McFadden G, Lucas A. Viral serpin therapeutics from concept to clinic. Methods Enzymol. 2011;499:301-29. PMID: 21683260.
  • Thoburn R. Evolution of the Kunkel phenotype. Lupus. 2003;12(3):231-7. PMID: 12708788.
  • Panush RS, Thoburn R. Should minocycline be used to treat rheumatoid arthritis? Bull Rheum Dis. 1996 Apr;45(2):2-5. Review. PMID: 8901389.

Abstracts:

  • Chen H, Zheng DH, Liu LY, Davids J, Williams J, Bartee MY, Reeves W, Sobel E, Thoburn R, Lucas A. Serpin Treatment Reduces Early Inflammation and Mortality in gamma 68 Herpes virus (g68HV) Infected Mice; A Vasculitis Model. Atheroscler Thromb Vasc Biol Meeting Chicago, April, 2011.
  • Chen H, Zheng DH, Liu LY, Samy H, Staples N, Beaver T, Hess P, Martin T, Klodel C, Ryden S, Weyland C, Reeves W, Thoburn R, Sobel, E, Lucas A. Xenografts from Bypass (lima  control) and Suspected Giant Cell Arteritis (GCA/TA) Patients in SCID Mice Have Reduced Inflammation with Serpin Treatment. Atheroscler Thromb Vasc Biol Meeting Chicago, April, 2011
  • Zeng D, Feldman E, Williams J, Daavids J, Liu LY, Reeves W, Sobel E, Thoburn R, Lucas A. Alteration of Gene Expression in Systemic Lupus Erythematosus (SLE) Patient Circulating mononuclear cells (PBMC) after Serpin Treatment. Atheroscler Thromb Vasc Biol Meeting Chicago, April, 2011.
  • Lucas A, Chan H, Zheng DH, Dai E, Liu LY, Samy H, Staples N, Beaver T, Hess P, Klodel C, Ryden S, Weyand C, Reeves W, Thoburn R, Sobel E,. Analysis of Myomaviral Serpin Treatment for Inflammatory Vasculitic Syndromes, Giant Cell and Takayasu Arteritis. World Heart Congress, Vancouver Canada, July 2011.

Please click here for a list of Dr. Thoburn’s industry relationships.