Shuhong Han

Shuhong Han,

Postdoctoral Associate

Department: MD-RHEUMATOLOGY
Business Phone: (352) 274-8217

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-6951-120X

Publications

2022
A novel monocyte differentiation pattern in pristane-induced lupus with diffuse alveolar hemorrhage
eLife. 11 [DOI] 10.7554/elife.76205.
2022
Author response: A novel monocyte differentiation pattern in pristane-induced lupus with diffuse alveolar hemorrhage
. [DOI] 10.7554/elife.76205.sa2.
2022
Microvascular lung injury and endoplasmic reticulum stress in systemic lupus erythematosus-associated alveolar hemorrhage and pulmonary vasculitis.
American journal of physiology. Lung cellular and molecular physiology. 323(6):L715-L729 [DOI] 10.1152/ajplung.00051.2022. [PMID] 36255715.
2021
Microscopic Polyangiitis With Diffuse Alveolar Hemorrhage and Glomerulonephritis Complicating Acute Influenza Infection.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 27(8S):S618-S619 [DOI] 10.1097/RHU.0000000000001730. [PMID] 33843777.
2021
Myxomavirus serpin alters macrophage function and prevents diffuse alveolar hemorrhage in pristane-induced lupus.
Clinical immunology (Orlando, Fla.). 229 [DOI] 10.1016/j.clim.2021.108764. [PMID] 34089860.
2021
Reply
Arthritis & Rheumatology. 73(1):176-178 [DOI] 10.1002/art.41478.
2020
Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon
Arthritis & Rheumatology. 72(1):100-113 [DOI] 10.1002/art.41072. [PMID] 31390156.
2020
NF‐E2–Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus
Arthritis & Rheumatology. 72(10):1707-1720 [DOI] 10.1002/art.41383. [PMID] 32500632.
2019
High-dimensional analysis reveals a pathogenic role of inflammatory monocytes in experimental diffuse alveolar hemorrhage
JCI Insight. 4(15) [DOI] 10.1172/jci.insight.129703. [PMID] 31391335.
2019
Irisin Attenuates Neuroinflammation and Prevents the Memory and Cognitive Deterioration in Streptozotocin-Induced Diabetic Mice.
Mediators of inflammation. 2019 [DOI] 10.1155/2019/1567179. [PMID] 31281225.
2019
The Association between Depression and Type 1 Diabetes Mellitus: Inflammatory Cytokines as Ferrymen in between?
Mediators of inflammation. 2019 [DOI] 10.1155/2019/2987901. [PMID] 31049023.
2018
Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages.
Frontiers in immunology. 9 [DOI] 10.3389/fimmu.2018.00135. [PMID] 29456535.
2017
A Novel Subset of Anti-Inflammatory CD138+ Macrophages Is Deficient in Mice with Experimental Lupus.
Journal of immunology (Baltimore, Md. : 1950). 199(4):1261-1274 [DOI] 10.4049/jimmunol.1700099. [PMID] 28696256.
2017
Pathogenesis of Diffuse Alveolar Hemorrhage in Murine Lupus.
Arthritis & rheumatology (Hoboken, N.J.). 69(6):1280-1293 [DOI] 10.1002/art.40077. [PMID] 28217966.
2016
“Lupoid hepatitis” in SLE patients and mice with experimental lupus.
Clinical immunology (Orlando, Fla.). 172:65-71 [DOI] 10.1016/j.clim.2016.07.007. [PMID] 27430519.
2016
A Novel Mechanism for Generating the Interferon Signature in Lupus: Opsonization of Dead Cells by Complement and IgM.
Arthritis & rheumatology (Hoboken, N.J.). 68(12):2917-2928 [DOI] 10.1002/art.39781. [PMID] 27274010.
2016
Lamotrigine Reduces Inflammatory Response and Ameliorates Executive Function Deterioration in an Alzheimer’s-Like Mouse Model.
BioMed research international. 2016 [DOI] 10.1155/2016/7810196. [PMID] 28042572.
2015
Animal Models of Interferon Signature Positive Lupus.
Frontiers in immunology. 6 [DOI] 10.3389/fimmu.2015.00291. [PMID] 26097482.
2015
Maintenance of autoantibody production in pristane-induced murine lupus.
Arthritis research & therapy. 17 [DOI] 10.1186/s13075-015-0886-9. [PMID] 26717913.
2015
Mechanisms of autoantibody production in systemic lupus erythematosus.
Frontiers in immunology. 6 [DOI] 10.3389/fimmu.2015.00228. [PMID] 26029213.
2015
Mechanisms of tumor necrosis factor α antagonist-induced lupus in a murine model.
Arthritis & rheumatology (Hoboken, N.J.). 67(1):225-37 [DOI] 10.1002/art.38882. [PMID] 25252121.
2015
STAT3 signaling contributes to the high effector activities of interleukin-15-derived dendritic cells.
Immunology and cell biology. 93(5):461-71 [DOI] 10.1038/icb.2014.103. [PMID] 25582338.
2014
Expression of recombinant human IL-4 in Pichia pastoris and relationship between its glycosylation and biological activity.
Protein expression and purification. 96:1-7 [DOI] 10.1016/j.pep.2014.01.005. [PMID] 24468271.
2014
Toll-like receptor 7-stimulated tumor necrosis factor α causes bone marrow damage in systemic lupus erythematosus.
Arthritis & rheumatology (Hoboken, N.J.). 66(1):140-51 [DOI] 10.1002/art.38189. [PMID] 24449581.
2013
Cd40 Exon 8 Deficiency Causes a Novel Form of Immunodeficiency With Hyper-Igm
Journal of Immunology. 190
2013
Novel autoantigens in type 1 diabetes.
American journal of translational research. 5(4):379-92 [PMID] 23724162.
2013
Novel detection of pancreatic and duodenal homeobox 1 autoantibodies (PAA) in human sera using luciferase immunoprecipitation systems (LIPS) assay.
International journal of clinical and experimental pathology. 6(6):1202-10 [PMID] 23696946.
2012
Characterization and Immunotherapeutic Implication of a Novel Cerebro-Spinal Fluid-Derived Alk-Positive Anaplastic Large Cell Lymphoma Cell Line
Blood. 120
2012
Pleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupus.
Journal of immunology (Baltimore, Md. : 1950). 188(8):4113-21 [DOI] 10.4049/jimmunol.1103113. [PMID] 22422888.
2012
The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance.
Chemico-biological interactions. 195(1):52-60 [DOI] 10.1016/j.cbi.2011.10.007. [PMID] 22079344.
2010
Ex vivo development, expansion and in vivo analysis of a novel lineage of dendritic cells from hematopoietic stem cells.
Journal of immune based therapies and vaccines. 8 [DOI] 10.1186/1476-8518-8-8. [PMID] 21106069.
2010
Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.
PloS one. 5(7) [DOI] 10.1371/journal.pone.0011726. [PMID] 20668510.
2009
Immunity of lentiviral vector-modified dendritic cells.
Methods in molecular biology (Clifton, N.J.). 542:245-59 [DOI] 10.1007/978-1-59745-561-9_13. [PMID] 19565906.
2009
Lentiviral calnexin-modified dendritic cells promote expansion of high-avidity effector T cells with central memory phenotype.
Immunology. 128(1):43-57 [DOI] 10.1111/j.1365-2567.2009.03067.x. [PMID] 19689735.
2009
Phenotype and functional evaluation of ex vivo generated antigen-specific immune effector cells with potential for therapeutic applications.
Journal of hematology & oncology. 2 [DOI] 10.1186/1756-8722-2-34. [PMID] 19660111.
2008
Overcoming immune tolerance against multiple myeloma with lentiviral calnexin-engineered dendritic cells.
Molecular therapy : the journal of the American Society of Gene Therapy. 16(2):269-79 [PMID] 18071334.

Grants

Sep 2017 – Aug 2023
PATHOGENESIS OF PRISTANE-INDUCED LUPUS
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Jul 2009 – Jun 2019
McKethan Professor Arthritis
Role: Principal Investigator
Funding: UF FOUNDATION

Contact Details

Phones:
Business:
(352) 274-8217
Emails:
Addresses:
Business Mailing:
DEPT. OF MEDICINE, DIVISION OF RHEUMATOLOGY
PO BOX 100221
ARB R2-156
GAINESVILLE FL 326100221